Phenylbutazone is FDA approved for use with horses and is a prescription drug. U. S. federal law restricts this drug to use by or on the lawful written or oral order of a licensed veterinarian. Phenylbutazone is a regulated or prohibited substance in most sanctioned competitions. In each case, the proper regulatory group should be consulted.. Phenylbutazone ("bute") is an anti-inflammatory drug—a non-steroidal anti-inflammatory drug (NSAID) similar to aspirin, Advil, Motrin, Banamine, etc. Bute has been used for many decades in horses to relieve pain, particularly in musculoskeletal injuries, navicular syndrome, arthritis, etc. It has been a comparatively safe and effective.

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Phenylbutazone (PBZ), commonly known as Bute, can be the horse owner's (and horse's) best friend. This popular and economical non-steroidal anti-inflammatory (NSAID) blocks pain, reduces swelling.. Phenylbutazone ("bute") is an anti-inflammatory drug—a non-steroidal anti-inflammatory drug (NSAID) similar to aspirin, Advil, Motrin, Banamine, etc. Bute has been used for many decades in horses to relieve pain, particularly in musculoskeletal injuries, navicular syndrome, arthritis, etc. It has been a comparatively safe and effective.